Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23600924 | 0.89 | ALDH1A1 (0.54) | KCNH2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL12299452 | 0.88 | KCNH2 (0.53) | KCNH2CYP1A2CYP2A6TAAR1DRD2 | |
| P-Xylene SCHEMBL27374298 | 0.87 | TSHR (0.50) | KCNH2MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9008786 | 0.87 | KCNH2 (0.59) | KCNH2CYP1A2CYP2A6TAAR1DRD2 | |
| P-Xylene SCHEMBL28282785 | 0.85 | TSHR (0.48) | KCNH2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL12873975 | 0.84 | KCNH2 (0.54) | KCNH2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL21175628 | 0.83 | CA2 (0.52) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL11104424 | 0.82 | MAPK1 (0.47) | KCNH2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL23182826 | 0.82 | TSHR (0.47) | KCNH2MEN1USP2ALDH1A1LMNA | |
| SCHEMBL8939444 | 0.82 | ESR1 (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |