Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765937 | 0.77 | PPARA (0.68) | PPARAPPARGSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL1690816 | 0.77 | NPC1 (0.82) | RAB9ANPC1SMN1; SMN2CA12CA9 | |
| SCHEMBL19002587 | 0.76 | HSD17B1 (0.56) | RAB9ANPC1KMT2A | |
| SCHEMBL346586 | 0.74 | PPARA (0.60) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL8368616 | 0.74 | CYP2D6 (0.53) | PLA2G4BBCHEACHE | |
| SCHEMBL15063356 | 0.74 | LMNA (0.74) | PPARAPPARGSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL14885505 | 0.74 | PPARA (0.63) | PPARAPPARGSMN1; SMN2CA12CA1 | |
| Hydrochloric Acid SCHEMBL9118273 | 0.73 | CYP2D6 (0.53) | PLA2G4BBCHEACHE | |
| SCHEMBL9502544 | 0.73 | PPARA (1.00) | PPARAPPARGLMNAPTGIRPLA2G4B | |
| SCHEMBL1635493 | 0.73 | PPARA (1.00) | PPARAPPARGLMNAPTGIRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |