Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358893 | 0.82 | SCN4A (0.46) | SCN4ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL12517837 | 0.80 | FFAR4 (0.41) | GAAALDH1A1PLAUMAPT | |
| SCHEMBL19940003 | 0.78 | PLAU (0.42) | GAAALDH1A1LMNAKMT2APLAU | |
| SCHEMBL19088279 | 0.78 | GAA (0.42) | SCN4AGAAALDH1A1TSHRLMNA | |
| SCHEMBL18726947 | 0.76 | CXCR5 (0.32) | MEN1KMT2ACXCR5PLAU | |
| SCHEMBL12180582 | 0.76 | LMNA (0.37) | LMNAMEN1KMT2AGABRA1PLAU | |
| SCHEMBL2544650 | 0.76 | LMNA (0.36) | ALDH1A1LMNAMEN1KMT2AGABRA1 | |
| SCHEMBL12401803 | 0.74 | POLB (0.43) | TSHRGABRA1PLAU | |
| SCHEMBL20624746 | 0.74 | GAA (0.40) | SCN4AGAAALDH1A1TSHRHTR2A | |
| SCHEMBL24779632 | 0.73 | TAS1R3 (0.37) | GAAALDH1A1TSHRPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481976-B1 | 8-AZAPROSTAGLANDIN DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-7226950-B2 | Sodium channel modulators | THERAVANCE, INC. (US) | 2007-06-05 | — | — | US | disclosed |