Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015592 | 0.95 | IL6 (0.44) | IL6KMT2A | |
| SCHEMBL14015601 | 0.94 | IL6 (0.46) | IL6FAAHDRD2DRD3KMT2A | |
| SCHEMBL13639351 | 0.92 | IL6 (0.46) | IL6KMT2A | |
| SCHEMBL14015809 | 0.90 | IL6 (0.46) | IL6KMT2A | |
| SCHEMBL14015559 | 0.90 | IL6 (0.45) | IL6KMT2A | |
| SCHEMBL14015532 | 0.88 | IL6 (0.44) | IL6KMT2AMAPK1 | |
| SCHEMBL13639338 | 0.88 | IL6 (0.51) | IL6 | |
| SCHEMBL13639303 | 0.88 | IL6 (0.47) | IL6KMT2A | |
| SCHEMBL13639319 | 0.87 | IL6 (0.48) | IL6FAAHDRD3 | |
| SCHEMBL14015603 | 0.86 | IL6 (0.46) | IL6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |
| EP-1995242-A1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | Santen Pharmaceutical Co., Ltd (JP) | 2008-11-26 | — | — | EP | disclosed |