Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14015809 | 0.94 | IL6 (0.46) | IL6MAPTKMT2APDCD1CD274 | |
| SCHEMBL14015601 | 0.91 | IL6 (0.46) | IL6MAPTLMNAKMT2APRNP | |
| SCHEMBL13639351 | 0.89 | IL6 (0.46) | IL6MAPTKMT2APRNP | |
| SCHEMBL14015532 | 0.88 | IL6 (0.44) | IL6MAPTLMNAKMT2A | |
| SCHEMBL13639348 | 0.88 | IL6 (0.44) | IL6KMT2A | |
| SCHEMBL13639338 | 0.87 | IL6 (0.51) | IL6MAPTLMNA | |
| SCHEMBL14015592 | 0.87 | IL6 (0.44) | IL6MAPTKMT2A | |
| SCHEMBL13639311 | 0.87 | IL6 (0.46) | IL6MAPTKMT2APDCD1CD274 | |
| SCHEMBL14015559 | 0.87 | IL6 (0.45) | IL6MAPTTHRBKMT2A | |
| SCHEMBL14015603 | 0.86 | IL6 (0.46) | IL6MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1995242-B1 | NOVEL 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE HAVING GLUCOCORTICOID RECEPTOR BINDING ACTIVITY | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-11-07 | — | — | EP | disclosed |