Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7950135 | 0.87 | MDM2 (0.40) | TP53MDM2 | |
| SCHEMBL13639644 | 0.80 | MDM2 (0.45) | TP53MDM2 | |
| SCHEMBL13639598 | 0.70 | MDM2 (0.31) | TP53MDM2 | |
| SCHEMBL30005751 | 0.70 | MDM2 (0.44) | TP53MDM2 | |
| SCHEMBL3373608 | 0.70 | MDM2 (0.45) | TP53MDM2 | |
| SCHEMBL30492739 | 0.70 | MDM2 (0.45) | TP53MDM2 | |
| SCHEMBL30006755 | 0.66 | MDM2 (0.40) | TP53MDM2 | |
| SCHEMBL30006600 | 0.65 | MDM2 (0.41) | TP53MDM2 | |
| SCHEMBL30006461 | 0.65 | MDM2 (0.42) | TP53MDM2 | |
| SCHEMBL30005629 | 0.65 | MDM2 (0.37) | TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340021-B1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 2012-11-07 | — | — | EP | disclosed |