Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 20/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30492739 | 1.00 | MDM2 (0.45) | MDM2TP53MDM4 | |
| SCHEMBL3373614 | 1.00 | MDM2 (0.45) | MDM2TP53MDM4 | |
| SCHEMBL30005751 | 0.94 | MDM2 (0.44) | MDM2TP53MDM4 | |
| SCHEMBL30006755 | 0.93 | MDM2 (0.40) | MDM2TP53MDM4 | |
| SCHEMBL30968811 | 0.93 | MDM2 (0.41) | MDM2TP53MDM4 | |
| SCHEMBL30006461 | 0.92 | MDM2 (0.42) | MDM2TP53MDM4 | |
| SCHEMBL30492677 | 0.91 | MDM2 (0.44) | MDM2TP53MDM4 | |
| SCHEMBL30968778 | 0.91 | MDM2 (0.40) | MDM2TP53MDM4 | |
| SCHEMBL30007161 | 0.90 | MDM2 (0.36) | MDM2TP53MDM4 | |
| SCHEMBL30005629 | 0.87 | MDM2 (0.37) | MDM2TP53MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | DING QINGJIE | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | MDM2 995/4885TP53 199/4885MDM4 2063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.