Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206642 | 0.89 | MAPK1 (0.47) | DHODHKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL10206659 | 0.86 | DHODH (0.41) | GRM5DHODHMAOADYRK1AHCRTR1 | |
| SCHEMBL2668141 | 0.85 | DHODH (0.41) | GRM5DHODHMAOADYRK1AHCRTR1 | |
| SCHEMBL10206641 | 0.83 | PRMT5 (0.51) | DHODHPRMT5MAPK1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL711040 | 0.81 | DHODH (0.45) | DHODHHCRTR1RAB9APRMT5MAPK1 | |
| Trifluoroacetic Acid SCHEMBL709569 | 0.79 | DHODH (0.43) | DHODHHCRTR1HPGDGCKGPR132 | |
| SCHEMBL709496 | 0.77 | PRMT5 (0.44) | PRMT5GCK | |
| SCHEMBL10206644 | 0.77 | PRMT5 (0.46) | DHODHPRMT5MAPK1 | |
| SCHEMBL10206658 | 0.77 | NOS3 (0.38) | DHODHIKBKBPRMT5GCK | |
| SCHEMBL711044 | 0.76 | GCK (0.46) | KDM4ENPC1ALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940837-B1 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2012-11-07 | — | — | EP | disclosed |