Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10206659 | 0.87 | DHODH (0.41) | DHODHGPR132ACACBHCRTR1KDM4E | |
| SCHEMBL13639545 | 0.85 | GRM5 (0.52) | DHODHGPR132HCRTR1KDM4ENPC1 | |
| SCHEMBL10206642 | 0.85 | MAPK1 (0.47) | DHODHKDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL10206641 | 0.79 | PRMT5 (0.51) | DHODHMAPK1PRMT5 | |
| SCHEMBL2668123 | 0.79 | GCK (0.42) | DHODHPRMT5 | |
| Trifluoroacetic Acid SCHEMBL709569 | 0.79 | DHODH (0.43) | DHODHGPR132ACACBHCRTR1HPGD | |
| SCHEMBL709496 | 0.78 | PRMT5 (0.44) | PRMT5 | |
| Trifluoroacetic Acid SCHEMBL711040 | 0.78 | DHODH (0.45) | DHODHGPR132HCRTR1RAB9AMAPK1 | |
| SCHEMBL10206658 | 0.78 | NOS3 (0.38) | DHODHIKBKBPRMT5 | |
| SCHEMBL711044 | 0.77 | GCK (0.46) | KDM4ENPC1ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028135-A2 | IMIDAZOPYRIDINE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-03-08 | — | — | WO | disclosed |