Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 3/20 | 0.53 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16400660 | 0.85 | PARP1 (0.56) | PARP1ERN1BAZ2BBAZ2APRKCI | |
| SCHEMBL4171236 | 0.84 | ALOX5 (0.60) | ALOX5ERN1CNR2 | |
| SCHEMBL6068002 | 0.83 | ALOX5 (0.53) | ALOX5TDP2FYNCNR2 | |
| SCHEMBL17175985 | 0.82 | PARP1 (0.56) | PARP1ERN1BAZ2BBAZ2APRKCI | |
| SCHEMBL1147444 | 0.82 | PARP1 (0.77) | PARP1ERN1FYN | |
| SCHEMBL16400571 | 0.82 | MKNK1 (0.58) | PARP1ERN1BAZ2BBAZ2AFYN | |
| SCHEMBL1788218 | 0.80 | PARP1 (0.62) | PARP1ERN1TDP2 | |
| SCHEMBL28150203 | 0.79 | ERN1 (0.53) | PARP1ERN1BAZ2BBAZ2APRKCI | |
| SCHEMBL31422694 | 0.79 | PARP1 (0.64) | PARP1ERN1TDP2 | |
| SCHEMBL2431097 | 0.79 | PARP1 (0.64) | PARP1ERN1TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948146-B1 | NOVEL MULTI-CYCLIC COMPOUNDS AND THEIR USE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2007039111-A2 | NOVEL MULTI-CYCLIC COMPOUNDS AND THEIR USE | REVOTAR BIOPHARMACEUTICALS AG (DE) | 2007-04-12 | — | — | WO | disclosed |