Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.56 |
| ▸ | ERN1 | O75460 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16400660 | 0.88 | PARP1 (0.56) | PARP1ERN1FAAHNPC1RAB9A | |
| SCHEMBL13639736 | 0.82 | PARP1 (0.61) | PARP1ERN1BAZ2BBAZ2APRKCI | |
| SCHEMBL1926792 | 0.82 | NPC1 (0.66) | PARP1ERN1FAAHNPC1RAB9A | |
| SCHEMBL1787719 | 0.82 | ERN1 (0.51) | PARP1ERN1NPC1RAB9AAR | |
| SCHEMBL17175628 | 0.81 | FAAH (0.56) | ERN1FAAH | |
| SCHEMBL24163691 | 0.80 | PARP1 (0.60) | PARP1ERN1FAAHNPC1RAB9A | |
| SCHEMBL28046033 | 0.79 | ERN1 (0.52) | PARP1ERN1FAAHNPC1RAB9A | |
| SCHEMBL1788340 | 0.78 | PARP1 (0.56) | PARP1ERN1NPC1RAB9AAR | |
| SCHEMBL1147444 | 0.78 | PARP1 (0.77) | PARP1ERN1FYN | |
| SCHEMBL17175624 | 0.77 | FAAH (0.57) | PARP1ERN1FAAHBAZ2BBAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015157313-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) ENZYME WITH IMPROVED ORAL BIOAVAILABILITY AND THEIR USE AS MEDICAMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-15 | — | — | WO | disclosed |