Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1372963 | 0.85 | HRH3 (0.74) | HRH3HTR3A | |
| SCHEMBL1372959 | 0.85 | HRH3 (0.74) | HRH3HTR3A | |
| SCHEMBL16588441 | 0.85 | HRH3 (0.66) | HRH3MAOAMAOBLMNANPY1R | |
| SCHEMBL10258996 | 0.82 | HRH3 (1.00) | HRH3LMNANPY1RNPY2RHTR3A | |
| SCHEMBL12017607 | 0.81 | HRH3 (0.98) | HRH3LMNANPY1RNPY2RHTR3A | |
| SCHEMBL14319716 | 0.75 | HTR3A (0.76) | HRH3HTR3A | |
| SCHEMBL27754184 | 0.75 | LMNA (0.47) | HRH3LMNANPY1RNPY2R | |
| SCHEMBL1376869 | 0.74 | HRH3 (0.69) | HRH3HTR3A | |
| SCHEMBL1375386 | 0.74 | HTR3A (0.78) | HRH3HTR3A | |
| SCHEMBL14419243 | 0.72 | KDM4E (0.59) | HRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-B1 | PYRIDIZINONE DERIVATIVES | CEPHALON INC (US) | 2012-11-07 | — | — | EP | disclosed |