Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | IL17A | Q16552 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14319716 | 0.83 | HTR3A (0.76) | HTR3AHRH3KCNH2 | |
| SCHEMBL1375386 | 0.82 | HTR3A (0.78) | HTR3AHRH3KCNH2 | |
| SCHEMBL14308933 | 0.81 | HTR3A (0.98) | HTR3AHRH3KCNH2 | |
| SCHEMBL10197092 | 0.80 | HTR3A (1.00) | HTR3AHRH3KCNH2 | |
| SCHEMBL1373384 | 0.71 | HRH3 (0.72) | HTR3AHRH3KCNH2 | |
| SCHEMBL1373387 | 0.71 | HRH3 (0.72) | HTR3AHRH3KCNH2 | |
| SCHEMBL10260801 | 0.69 | HTR3A (0.71) | HTR3AHRH3 | |
| SCHEMBL12017517 | 0.69 | HRH3 (0.67) | HTR3AHRH3KCNH2 | |
| SCHEMBL24163014 | 0.69 | L3MBTL1 (0.71) | ALDH1A1HRH3HTR1AHTR2AHTR7 | |
| SCHEMBL1373734 | 0.68 | HRH3 (0.82) | HTR3AHRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-B1 | PYRIDIZINONE DERIVATIVES | CEPHALON INC (US) | 2012-11-07 | — | — | EP | disclosed |