Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416995 | 0.83 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19HTTPSENEN | |
| SCHEMBL18341304 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL18340826 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL18340827 | 0.83 | CYP1A2 (0.51) | CYP1A2CYP2C9CYP2C19HTTNFKB1 | |
| SCHEMBL14416977 | 0.82 | PSENEN (0.42) | PSENENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2408130 | 0.81 | CTSK (0.55) | CYP1A2CYP2C9CYP2C19HTTPSENEN | |
| SCHEMBL2408132 | 0.81 | CTSK (0.55) | CYP1A2CYP2C9CYP2C19HTTPSENEN | |
| SCHEMBL3058483 | 0.79 | CTSK (0.41) | CYP1A2CYP2C9CYP2C19HTTPSENEN | |
| SCHEMBL10538884 | 0.79 | SMN1; SMN2 (0.41) | PSENENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5886446 | 0.78 | CTSK (0.46) | PSENENCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524925-B1 | LANTHIONINE DERIVATIVE | AJINOMOTO KK (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-8568814-B2 | Lanthionine derivatives | AJINOMOTO CO., INC. (JP) | 2013-10-29 | — | — | US | disclosed |
| EP-2524925-A1 | LANTHIONINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120282386-A1 | LANTHIONINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282386-A1 | LANTHIONINE DERIVATIVES | CASR, KCNJ5, CALCR | CYP1A2 4081/4885CYP2C9 4005/4885CYP2C19 4199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.