Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 4/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 5/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408132 | 0.87 | CTSK (0.55) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2408130 | 0.87 | CTSK (0.55) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14416977 | 0.83 | PSENEN (0.42) | CTSKCTSSRENCTSDPSENEN | |
| SCHEMBL1763873 | 0.82 | CYP1A2 (0.49) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2225458 | 0.82 | CYP1A2 (0.49) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1317487 | 0.82 | CYP1A2 (0.49) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16383328 | 0.82 | CTSK (0.47) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30407324 | 0.81 | REN (0.44) | CTSKCTSSCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10144106 | 0.81 | PSENEN (0.45) | CTSKCTSSRENCTSDPSENEN | |
| SCHEMBL20732234 | 0.81 | CTSK (0.44) | CTSKCTSSCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7704957-B2 | Composition for inhibiting HIV activity extracted from Paecilomyces sp. (Tochu-kaso) J300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2010-04-27 | — | — | US | disclosed |
| US-7704957-B2 | Composition for inhibiting HIV activity extracted from Paecilomyces sp. (Tochu-kaso) J300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2010-04-27 | — | — | US | disclosed |
| US-20040121963-A1 | Composition for inhibiting hiv activity extracted from paecilomyces sp. (tochu-kaso) j300 | RURAL DEVELOPMENT ADMINISTRATION (KR) | 2004-06-24 | — | — | US | disclosed |
| EP-1389111-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM i PAECILOMYCES SP. /i (TOCHU-KASO) J300 | Republic of Korea (KR) | 2004-02-18 | — | — | EP | disclosed |
| WO-2002080921-A1 | COMPOSITION FOR INHIBITING HIV ACTIVITY EXTRACTED FROM PAECILOMYCES SP. (TOCHU-KASO) J300 | REPUBLIC OF KOREA (KR) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121963-A1 | Composition for inhibiting hiv activity extracted from paecilomyces sp. (tochu-kaso) j300 | KMO, JMJD1C, KYAT3 | CTSK 4521/4885CTSS 4080/4885CYP1A2 1252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.