Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267957 | 0.89 | CYP3A4 (0.71) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL13640727 | 0.83 | KDM4E (0.67) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL29651565 | 0.81 | KDM4E (0.56) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL1742326 | 0.76 | KDM4E (0.52) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL13640733 | 0.76 | CYP3A4 (0.81) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL28467498 | 0.75 | MAOA (0.54) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL11622418 | 0.74 | MAOB (0.54) | MAOAMAOB | |
| SCHEMBL571121 | 0.74 | SMN1; SMN2 (0.72) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL30176086 | 0.74 | ABCB1 (0.59) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 | |
| SCHEMBL13640726 | 0.73 | MIF (0.61) | KDM4ECYP3A4ALDH1A1RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | NORTHWESTERN UNIVERSITY (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | MAPK4, MAP4K4, MAP3K4 | KDM4E 242/4885CYP3A4 557/4885ALDH1A1 1204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.