Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 9/20 | 0.54 |
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoflavone SCHEMBL6290885 | 0.86 | ALDH1A1 (0.66) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL6542422 | 0.86 | ALDH1A1 (0.66) | MIFMAPTMAOBMAOAALOX12 | |
| SCHEMBL8338813 | 0.86 | PIN1 (0.46) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL8028 | 0.86 | ALDH1A1 (0.66) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL31264756 | 0.86 | ALDH1A1 (0.66) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL27523008 | 0.85 | ALDH1A1 (0.65) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL5846515 | 0.84 | ALDH1A1 (0.64) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL5846511 | 0.84 | ALDH1A1 (0.64) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL5854324 | 0.84 | ALDH1A1 (0.64) | MIFMAPTMAOBMAOAALOX12 | |
| Isoflavone SCHEMBL27846670 | 0.84 | ALDH1A1 (0.64) | MIFMAPTMAOBMAOAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400568-B | 7-aryloxy acetoxyl isoflavone derivative and application thereof in pesticides | 江苏大学 | 2022-10-25 | — | — | CN | disclosed |
| US-9573921-B2 | Substituted N, N-dimethylaminoalkyl ethers of isoflavanone oximes as H1-receptor antagonists | POLFARMEX S.A. (PL) | 2017-02-21 | — | — | US | disclosed |
| US-20160237055-A1 | NOVEL SUBSTITUTED N, N-DIMETHYLAMINOALKYL ETHERS OF ISOFLAVANONE OXIMES AS H1-RECEPTOR ANTAGONISTS | POLFARMEX S.A. (PL) | 2016-08-18 | — | — | US | disclosed |
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | NORTHWESTERN UNIVERSITY (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237055-A1 | NOVEL SUBSTITUTED N, N-DIMETHYLAMINOALKYL ETHERS OF ISOFLAVANONE OXIMES AS H1-RECEPTOR ANTAGONISTS | HRH4, HRH1, HRH3 | MIF 2524/4885MAPT 4765/4885MAOB 937/4885 |
| US-20120283313-A1 | INHIBITION AND TREATMENT OF PROSTATE CANCER METASTASIS | MAPK4, MAP4K4, MAP3K4 | MIF 574/4885MAPT 2493/4885MAOB 2694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.