⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763937 | 0.82 | ALDH1A1 (0.34) | — | |
| SCHEMBL13734950 | 0.76 | CYP11B1 (0.30) | — | |
| SCHEMBL12203385 | 0.76 | ALDH1A1 (0.33) | — | |
| SCHEMBL15100969 | 0.76 | BAZ2B (0.37) | — | |
| SCHEMBL25619302 | 0.74 | PTGS1 (0.31) | — | |
| SCHEMBL20813280 | 0.74 | GRIN2A (0.34) | — | |
| SCHEMBL17942404 | 0.74 | — | — | |
| SCHEMBL16962902 | 0.74 | — | — | |
| SCHEMBL22275230 | 0.74 | — | — | |
| SCHEMBL2216049 | 0.74 | HCAR3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930595-A | Synthetic process of isoxazoline derivative | 江苏剑牌农化股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| EP-4653423-A1 | PYRAZOL-5-ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC Nantong Chemical Co., Ltd. (CN) | 2025-11-26 | — | — | EP | disclosed |
| US-20250326773-A1 | MRGPRX2 ANTAGONISTS, PHARMACEUTICAL COMPOSITION INCLUDING MRGPRX2 ANTAGONIST, AND METHOD OF TREATING MRGPRX2-MEDIATED DISEASE OR DISORDER | KYORIN SEIYAKU KK (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250326772-A1 | MRGPRX2 ANTAGONISTS, PHARMACEUTICAL COMPOSITION INCLUDING MRGPRX2 ANTAGONIST, AND METHOD OF TREATING MRGPRX2-MEDIATED DISEASE OR DISORDER | KYORIN SEIYAKU KK (JP) | 2025-10-23 | — | — | US | disclosed |
| CN-119930595-A | Synthetic process of isoxazoline derivative | 江苏剑牌农化股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119930595-A | Synthetic process of isoxazoline derivative | 江苏剑牌农化股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119591545-A | Synthesis method of difluoro pyrazole acid and ester and intermediate thereof | 湖北晟康化工有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-119504589-A | Method for synthesizing Isoflucypram intermediate | 山西玉龙化工有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2024199260-A1 | PYRAZOL-5-ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 南通泰禾化工股份有限公司 | 2024-10-03 | — | — | WO | disclosed |
| CN-118702628-A | Pyrazole-5-ether compound as well as preparation method and application thereof | 南通泰禾化工股份有限公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-20070015764-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20070015764-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2007-01-18 | — | — | US | disclosed |
| US-20070015764-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2007-01-18 | — | — | US | disclosed |
| US-7151105-B2 | Inhibitors of Hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. (US) | 2006-12-19 | — | — | US | disclosed |
| US-20060122399-A1 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. | 2006-06-08 | — | — | US | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |
| US-20050256004-A1 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1364946-A1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-11-26 | — | — | EP | disclosed |