SCHEMBL13643152

SCHEMBL13643152

c1ccc(-c2ccc(-c3cc4c(-c5ccc6c7ccccc7c7ccccc7c6c5)cc(-c5ccc6c7ccccc7c7ccccc7c6c5)nc4c4ccccc34)cc2)nc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 2/20 0.44
PIM1 P11309 1/20 0.40
PIM3 Q86V86 1/20 0.40
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TOP1 P11387 4/20 0.38
PRMT5 O14744 2/20 0.38
WDR77 Q9BQA1 1/20 0.38
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
PI4KA P42356 1/20 0.37
PIK3CG P48736 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
ACACA Q13085 2/20 0.36
CYP2A6 P11509 1/20 0.36
PDK2 Q15119 1/20 0.36
AURKA O14965 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13642842 1.00 DHODH (0.44) DHODHPIM1PIM3TSHRMAPK1
SCHEMBL13642984 0.97 DHODH (0.46) DHODHPIM1PIM3TSHRMAPK1
SCHEMBL13642996 0.89 DHODH (0.51) DHODHTSHRMAPK1HSD17B10TOP1
SCHEMBL13643172 0.89 DHODH (0.51) DHODHTSHRMAPK1HSD17B10TOP1
SCHEMBL13642857 0.89 DHODH (0.51) DHODHTSHRMAPK1HSD17B10TOP1
SCHEMBL13084034 0.88 ALDH1A1 (0.45) DHODHPIM1TSHRMAPK1HSD17B10
SCHEMBL13643067 0.88 ALDH1A1 (0.45) DHODHPIM1TSHRMAPK1HSD17B10
SCHEMBL13642796 0.87 DHODH (0.50) DHODHTSHRMAPK1HSD17B10TOP1
SCHEMBL13642956 0.87 DHODH (0.50) DHODHTSHRMAPK1HSD17B10TOP1
SCHEMBL13643096 0.87 DHODH (0.50) DHODHTSHRMAPK1HSD17B10TOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508585-B1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT EMITTING DIODE CHEIL IND INC (KR) 2016-06-29 EP disclosed
US-8796917-B2 Compound for an organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode CHEIL INDUSTRIES, INC (KR) 2014-08-05 US disclosed
US-8796917-B2 Compound for an organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode CHEIL INDUSTRIES, INC (KR) 2014-08-05 US disclosed
US-20120280613-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-11-08 US disclosed
US-20120280613-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120280613-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, OR10J3 DHODH 55/4885PIM1 1755/4885PIM3 3588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.