Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2617444 | 1.00 | ATM (0.39) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL13643257 | 0.87 | ATM (0.38) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL2617443 | 0.87 | ATM (0.38) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL2630586 | 0.85 | ATM (0.39) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL2617436 | 0.84 | ATM (0.37) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL13163317 | 0.84 | ATM (0.37) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL2617420 | 0.83 | ATM (0.41) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL13430535 | 0.83 | ATM (0.40) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL2617425 | 0.83 | ATM (0.40) | ATMCTSSCTSKPTPRBSCN9A | |
| SCHEMBL13627141 | 0.82 | ATM (0.42) | ATMCTSSCTSKPTPRBSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | ATM 1110/4885CTSS 1766/4885CTSK 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.