Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17897619 | 0.92 | POLB (0.54) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL16804562 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL11912127 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL18926373 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL10098927 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ATSHRPOLB | |
| SCHEMBL13702393 | 0.75 | PLK1 (0.66) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL12084220 | 0.74 | NPC1 (0.49) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL12665586 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL11947938 | 0.73 | POLB (0.75) | ALDH1A1MEN1KMT2AGAAPOLB | |
| SCHEMBL10098930 | 0.72 | PLK1 (0.56) | ALDH1A1MEN1KMT2ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283407-A1 | New polyamide, polyimide or polyamide-imide comprising dibenzodiazocine units | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2012-11-08 | — | — | US | disclosed |