SCHEMBL13645001

SCHEMBL13645001

Nc1ccc(N(CC(=O)O)CC(=O)Nc2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
CA1 P00915 4/20 0.49
CA2 P00918 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
RAB9A P51151 2/20 0.49
NPC1 O15118 1/20 0.49
NOX1 Q9Y5S8 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL889852 0.89 MEN1 (0.51) CA1CA2MEN1KMT2ARAB9A
SCHEMBL13644980 0.86 CA1 (0.50) CA1CA2MEN1KMT2ARAB9A
SCHEMBL3836570 0.84 MEN1 (0.56) MEN1KMT2ARAB9ANPC1NOX1
SCHEMBL341751 0.83 TDP1 (0.50) LMNAMEN1KMT2ARAB9AL3MBTL1
SCHEMBL13645024 0.81 ALDH1A1 (0.47) LMNACA1CA2MEN1KMT2A
SCHEMBL13603912 0.81 ALDH1A1 (0.56) LMNAMEN1KMT2ARAB9ANPC1
SCHEMBL13603928 0.80 KMT2A (0.57) LMNAMEN1KMT2ARAB9ANPC1
SCHEMBL651392 0.80 GAA (0.54) CA2MEN1KMT2ARAB9ANPC1
SCHEMBL11913585 0.80 KDM1A (0.51) LMNAMEN1KMT2ARAB9ANPC1
SCHEMBL9514501 0.78 CA1 (0.68) CA1CA2RAB9AMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed