Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.68 |
| ▸ | CA2 | P00918 | 17/20 | 0.68 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA9 | Q16790 | 3/20 | 0.60 |
| ▸ | CA4 | P22748 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19663826 | 0.92 | CA1 (0.70) | CA1CA2CA12CA9CA4 | |
| SCHEMBL9974560 | 0.84 | CA1 (0.64) | CA1CA2CA12CA9CA4 | |
| SCHEMBL9515833 | 0.83 | CA2 (0.63) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6325836 | 0.83 | ALDH1A1 (0.69) | CA1CA2MAPTRAB9ATDP1 | |
| SCHEMBL15499792 | 0.82 | CA1 (0.75) | CA1CA2CA12CA9CA4 | |
| Iprofenin SCHEMBL486656 | 0.82 | CA1 (0.58) | CA1CA2CA12CA9CA4 | |
| SCHEMBL8099868 | 0.80 | MAPT (0.59) | CA1CA2CA12CA9CA4 | |
| SCHEMBL9617679 | 0.79 | BCHE (0.62) | CA1CA2CA12CA9CA4 | |
| SCHEMBL486751 | 0.79 | CA1 (0.58) | CA1CA2CA12CA9CA4 | |
| SCHEMBL1409656 | 0.79 | MAPT (0.66) | CA1CA2MAPTRAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290041-B1 | Radioactive metal chelates of dipyridoxyl phosphate | NYCOMED SALUTAR INC (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4842845-A | Radioactive metal chelates for dipyridoxyl phosphate | SALUTAR, INC. (US) | 1989-06-27 | — | — | US | disclosed |
| EP-0290041-A2 | Radioactive metal chelates of dipyridoxyl phosphate | NYCOMED SALUTAR, INC. (US) | 1988-11-09 | — | — | EP | disclosed |