Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 13/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438396 | 0.90 | NPC1 (0.57) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16598803 | 0.90 | FAAH (0.64) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2219964 | 0.89 | GPR183 (0.57) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL12513600 | 0.89 | FAAH (0.63) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL12438409 | 0.89 | NPC1 (0.56) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL1135024 | 0.89 | NPC1 (0.56) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL12438404 | 0.89 | NPC1 (0.56) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL2220446 | 0.86 | NPC1 (0.53) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL16598448 | 0.82 | KDM4E (0.66) | MEN1LMNAKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL16599203 | 0.81 | MEN1 (0.66) | NPC1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129573-A1 | NICOTINAMIDE DERIVATIVES | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2009-10-29 | — | — | WO | disclosed |