Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16598803 | 0.90 | FAAH (0.64) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL12438396 | 0.90 | NPC1 (0.57) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL1135024 | 0.89 | NPC1 (0.56) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2219964 | 0.89 | GPR183 (0.57) | FAAHALDH1A1NPC1PRKAB2PRKAG1 | |
| SCHEMBL12438404 | 0.89 | NPC1 (0.56) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL12438409 | 0.89 | NPC1 (0.56) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL13645262 | 0.89 | NPC1 (0.56) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL2220446 | 0.88 | NPC1 (0.53) | FAAHNPC1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL16598448 | 0.82 | KDM4E (0.66) | KDM4EALDH1A1POLBLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10334549 | 0.81 | POLB (0.62) | FAAHKDM4EALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178396-A1 | Nicotinamide Derivatives | CRC FOR BIOMEDICAL IMAGING DEVELOPMENT LTD. (AU) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178396-A1 | Nicotinamide Derivatives | NAMPT, NNT, NNMT | FAAH 936/4885KDM4E 1275/4885ALDH1A1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.