Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400992 | 0.81 | CHRM3 (0.50) | CHRM3 | |
| SCHEMBL1632732 | 0.78 | SLC2A1 (0.38) | CHRM3SLC2A1 | |
| SCHEMBL1364552 | 0.77 | CHRM3 (0.47) | CHRM3 | |
| SCHEMBL1631046 | 0.72 | DPP4 (0.39) | CHRM3SLC2A1 | |
| SCHEMBL1630333 | 0.72 | CHRM3 (0.54) | CHRM3 | |
| SCHEMBL1365235 | 0.69 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL3411496 | 0.69 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL1631464 | 0.68 | CHRM3 (0.70) | CHRM3 | |
| SCHEMBL1362605 | 0.66 | LOXL2 (0.40) | — | |
| SCHEMBL1362267 | 0.66 | CHRM3 (0.42) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067408-B2 | Dual pharmacophores—PDE4-muscarinic antagonistics | GLAXO GROUP LIMITED (GB) | 2011-11-29 | — | — | US | disclosed |