Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10279909 | 0.85 | ATM (0.48) | ATMSLC16A3ESR2POLBKDM4E | |
| SCHEMBL10238298 | 0.84 | ATM (0.47) | ATMSLC16A3SMN1; SMN2POLBKMT2A | |
| SCHEMBL13645618 | 0.81 | KMT2A (0.49) | SLC16A3ESR2MAPK1KMT2ATDP1 | |
| SCHEMBL12798733 | 0.79 | ATM (0.41) | ATMSMN1; SMN2POLBKMT2ANAMPT | |
| SCHEMBL646049 | 0.78 | ATM (0.53) | ATMSMN1; SMN2POLBKMT2ANAMPT | |
| SCHEMBL645503 | 0.78 | ATM (0.76) | ATMSMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL16133857 | 0.78 | ATM (0.53) | ATMSMN1; SMN2POLBKMT2ANAMPT | |
| SCHEMBL647342 | 0.77 | ATM (0.52) | ATMSMN1; SMN2POLBKMT2ANAMPT | |
| SCHEMBL3863550 | 0.77 | SMN1; SMN2 (0.57) | ATMSLC16A3SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL13292708 | 0.77 | ALDH1A1 (0.44) | SLC16A3SMN1; SMN2ESR2MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598389-B2 | Silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20070191454-A1 | Silylated carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191454-A1 | Silylated carboxamides | MRPL21, MRPS22, MRPS34 | ATM 4099/4885SLC16A3 3515/4885SMN1; SMN2 2141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.