Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697417 | 0.83 | BRAF (0.31) | — | |
| SCHEMBL12456245 | 0.79 | PAK4 (0.35) | CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL13295543 | 0.77 | CYP1A2 (0.31) | CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL2325696 | 0.77 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL24908100 | 0.77 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL1085685 | 0.77 | KDM4E (0.34) | CYP1A2CYP2C19LMNA | |
| SCHEMBL19403253 | 0.77 | CYP1A2 (0.32) | CYP1A2CYP2C19 | |
| SCHEMBL19403175 | 0.77 | CYP1A2 (0.32) | CYP1A2CYP2C19 | |
| SCHEMBL20934269 | 0.76 | CYP1A2 (0.30) | CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL23869550 | 0.76 | CYP1A2 (0.30) | CYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9545105-B2 | 1-(heterocyclic carbonyl) piperidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-17 | — | — | US | disclosed |
| US-20130261155-A1 | 1-(HETEROCYCLIC CARBONYL) PIPERIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | US | disclosed |
| US-7598389-B2 | Silylated carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-10-06 | — | — | US | disclosed |
| US-7501527-B2 | Method for the production of fluoromethyl-substituted heterocycles | BAYER CROPSCIENCE GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-20070191454-A1 | Silylated carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
| US-20070191454-A1 | Silylated carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261155-A1 | 1-(HETEROCYCLIC CARBONYL) PIPERIDINES | CBR3, CBR1, CYP51A1 | COMT 2135/4885CYP1A2 23/4885CYP2C19 130/4885 |
| US-20070191454-A1 | Silylated carboxamides | MRPL21, MRPS22, MRPS34 | COMT 1522/4885CYP1A2 740/4885CYP2C19 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.