Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | CTH | P32929 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086231 | 0.76 | SMN1; SMN2 (0.35) | SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL3254686 | 0.71 | — | — | |
| SCHEMBL3254688 | 0.71 | RAB9A (0.33) | SMN1; SMN2RAB9ANPC1LMNARXFP1 | |
| SCHEMBL3251664 | 0.71 | GAA (0.34) | KDM4ESMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL28855633 | 0.70 | — | — | |
| SCHEMBL21803165 | 0.69 | LMNA (0.33) | SMN1; SMN2LMNATSHR | |
| SCHEMBL21803166 | 0.69 | LMNA (0.33) | SMN1; SMN2LMNATSHR | |
| SCHEMBL1197539 | 0.69 | — | — | |
| SCHEMBL16178297 | 0.67 | — | — | |
| SCHEMBL5697417 | 0.65 | BRAF (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164831-B1 | METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES | BASF SE (DE) | 2013-07-17 | — | — | EP | disclosed |
| CN-101679282-B | Process for producing N-substituted (3-dihalomethyl-1-methylpyrazol-4-yl) carboxamides | BASF SE | 2012-11-28 | — | — | CN | disclosed |
| US-8153820-B2 | Method for the production of N-substituted (3-dihalomethyl-1-methylpyrazol-4-yl) carboxamides | BASF SE (DE) | 2012-04-10 | — | — | US | disclosed |
| US-20100174094-A1 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides | BASF SE (DE) | 2010-07-08 | — | — | US | disclosed |
| EP-2164831-A1 | METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES | Basf Se (DE) | 2010-03-24 | — | — | EP | disclosed |
| CN-101679282-A | Process for producing N-substituted (3-dihalomethyl-1-methylpyrazol-4-yl) carboxamides | BASF SE | 2010-03-24 | — | — | CN | disclosed |
| WO-2008145740-A1 | METHOD FOR THE PRODUCTION OF N-SUBSTITUTED (3-DIHALOMETHYL-1-METHYL-PYRAZOLE-4-YL) CARBOXAMIDES | BASF SE (DE) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174094-A1 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides | CBR3, CBR1, CYC1 | KDM4E 1700/4885SMN1; SMN2 3019/4885RAB9A 2876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.