Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 17/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.51 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.47 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451668 | 0.95 | HSP90AB1 (0.49) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL10917478 | 0.90 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL4950742 | 0.89 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL10917174 | 0.89 | HSP90AB1 (0.52) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL10507394 | 0.88 | HSP90AB1 (0.48) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL8649570 | 0.81 | HSP90AB1 (0.55) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL30114962 | 0.81 | KDM4E (0.67) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL3155583 | 0.81 | KDM4E (0.67) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL6153979 | 0.81 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL3156963 | 0.80 | KDM4E (0.67) | HSP90AB1HSP90AA1HDAC6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101195622-A | Process for the preparation of famciclovir | FANGXIA ENTPR INF CONSULT CO (CN) | 2008-06-11 | — | — | CN | claimed |
| CN-108314685-B | Preparation method of 2-amino-6-chloro-9- (4-acetoxyl-3-acetoxymethyl butyl) purine | 上药康丽（常州）药业有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-108484605-B | Preparation method of 2-amino-6-chloro-9- (4-acetoxyl-3-acetoxymethyl butyl) purine | 上药康丽（常州）药业有限公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-101233134-B | Preparation of famciclovir and other purine derivatives | ARROW INT LTD | 2013-01-23 | — | — | CN | disclosed |
| US-7601835-B2 | Preparation of famciclovir and other purine derivatives | ARROW INTERNATIONAL LIMITED (MT) | 2009-10-13 | — | — | US | disclosed |
| US-7601835-B2 | Preparation of famciclovir and other purine derivatives | ARROW INTERNATIONAL LIMITED (MT) | 2009-10-13 | — | — | US | disclosed |
| CN-101233134-A | Preparation of famciclovir and other purine derivatives | ARROW INT LTD (MT) | 2008-07-30 | — | — | CN | disclosed |
| CN-101195622-A | Process for the preparation of famciclovir | FANGXIA ENTPR INF CONSULT CO (CN) | 2008-06-11 | — | — | CN | disclosed |
| CN-101195622-A | Process for the preparation of famciclovir | FANGXIA ENTPR INF CONSULT CO (CN) | 2008-06-11 | — | — | CN | disclosed |