Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 17/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645718 | 0.95 | HSP90AB1 (0.51) | HSP90AB1HSP90AA1CYP2C19HSP90B1TRAP1 | |
| SCHEMBL10917478 | 0.88 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL10917174 | 0.87 | HSP90AB1 (0.52) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL10507394 | 0.86 | HSP90AB1 (0.48) | HSP90AB1HSP90AA1CYP2C19HSP90B1TRAP1 | |
| SCHEMBL4950742 | 0.85 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL8649570 | 0.79 | HSP90AB1 (0.55) | HSP90AB1HSP90AA1HSP90B1TRAP1HDAC6 | |
| SCHEMBL6153979 | 0.79 | HSP90AB1 (0.50) | HSP90AB1HSP90AA1CYP2C19HSP90B1TRAP1 | |
| SCHEMBL30114962 | 0.79 | KDM4E (0.67) | HSP90AB1HSP90AA1CYP2C19HSP90B1TRAP1 | |
| SCHEMBL3155583 | 0.79 | KDM4E (0.67) | HSP90AB1HSP90AA1CYP2C19HSP90B1TRAP1 | |
| SCHEMBL6770698 | 0.78 | HSP90AB1 (0.48) | HSP90AB1HSP90AA1CYP2C19HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112979653-A | Method for synthesizing famciclovir by using microchannel reactor | 上药康丽（常州）药业有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-108314685-B | Preparation method of 2-amino-6-chloro-9- (4-acetoxyl-3-acetoxymethyl butyl) purine | 上药康丽（常州）药业有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-108484605-B | Preparation method of 2-amino-6-chloro-9- (4-acetoxyl-3-acetoxymethyl butyl) purine | 上药康丽（常州）药业有限公司 | 2020-08-21 | — | — | CN | disclosed |