Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240180 | 0.94 | RAB9A (0.54) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL2764014 | 0.83 | HPGD (0.63) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL9911662 | 0.82 | RAB9A (0.60) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL5338937 | 0.81 | RAB9A (0.58) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL18002724 | 0.81 | RAB9A (0.61) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL15871928 | 0.78 | RAB9A (0.58) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL13144514 | 0.76 | MAPT (0.70) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL8345149 | 0.76 | RAB9A (0.69) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL12582252 | 0.76 | RAB9A (0.72) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL201788 | 0.75 | RAB9A (0.67) | RAB9AGAAMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131952-A1 | COMPOUNDS, COMPOSITIONS AND METHODS COMPRISING THIAZOLE DERIVATIVES | INSTITUTE FOR ONEWORLD HEALTH (US) | 2009-10-29 | — | — | WO | disclosed |