Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240180 | 0.86 | RAB9A (0.54) | HPGDTSHRRAB9AGAAMAPT | |
| SCHEMBL27995668 | 0.85 | EGFR (0.60) | ALDH1A1HDAC3HDAC1HDAC7HDAC8 | |
| SCHEMBL13645752 | 0.83 | RAB9A (0.51) | HPGDTSHRRAB9AGAAMAPT | |
| SCHEMBL4600962 | 0.82 | ALDH1A1 (0.72) | HPGDGAAALDH1A1HDAC3HDAC1 | |
| SCHEMBL1683629 | 0.81 | EGFR (0.69) | ALDH1A1HDAC3HDAC1HDAC7HDAC8 | |
| SCHEMBL13144514 | 0.80 | MAPT (0.70) | HPGDTSHRRAB9AGAAMAPT | |
| SCHEMBL5338937 | 0.80 | RAB9A (0.58) | RAB9AGAAMAPTALDH1A1NPC1 | |
| SCHEMBL12582252 | 0.80 | RAB9A (0.72) | TSHRRAB9AGAAMAPTALDH1A1 | |
| SCHEMBL201788 | 0.79 | RAB9A (0.67) | HPGDRAB9AGAAMAPTALDH1A1 | |
| SCHEMBL2763747 | 0.78 | MAPT (0.51) | HPGDTSHRGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |