SCHEMBL13645837

SCHEMBL13645837

Fc1ccc2nc(-c3ccc(-c4c5ccccc5c(-c5ccc(-c6nc7ccc(F)cc7s6)cc5)c5c(-c6ccccc6)c6ccccc6c(-c6ccccc6)c45)cc3)sc2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 13/20 0.60
SULT1A1 P50225 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.52
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
GLA P06280 1/20 0.52
GAA P10253 1/20 0.52
PKM P14618 1/20 0.52
HPGD P15428 1/20 0.52
KMT2A Q03164 1/20 0.52
LMNA P02545 1/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
MAOB P27338 1/20 0.48
SLC11A2 P49281 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13645816 0.88 KDM4E (0.56) APPSULT1A1SMN1; SMN2KDM4EMAPT
SCHEMBL2139108 0.87 APP (0.71) APPSULT1A1SMN1; SMN2KDM4EMAPT
SCHEMBL14521862 0.85 APP (0.55) APPSULT1A1SMN1; SMN2KDM4EMAPT
SCHEMBL1100094 0.84 MAPT (0.60) APPSMN1; SMN2KDM4EMAPTMEN1
SCHEMBL13645798 0.84 MAPT (0.60) APPSMN1; SMN2KDM4EMAPTMEN1
SCHEMBL13645790 0.84 MAPT (0.60) APPSMN1; SMN2KDM4EMAPTMEN1
SCHEMBL6704183 0.83 RAB9A (0.59) APPSMN1; SMN2KDM4EMAPTMEN1
SCHEMBL13645860 0.83 MAPT (0.59) APPSMN1; SMN2KDM4EMAPTMEN1
SCHEMBL13645731 0.82 KDM4E (0.50) APPSMN1; SMN2KDM4EMAPTMEN1
SCHEMBL14191584 0.82 MAPT (0.58) APPSMN1; SMN2KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598666-B2 Organic electroluminescent device and luminescent material SANYO ELECTRIC CO., LTD. (JP) 2009-10-06 US disclosed
US-7598666-B2 Organic electroluminescent device and luminescent material SANYO ELECTRIC CO., LTD. (JP) 2009-10-06 US disclosed