SCHEMBL13645816

SCHEMBL13645816

c1ccc(-c2ccc3nc(-c4ccc(-c5c6ccccc6c(-c6ccc(-c7nc8ccc(-c9ccccc9)cc8s7)cc6)c6c(-c7ccccc7)c7ccccc7c(-c7ccccc7)c56)cc4)sc3c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.56
GAA P10253 6/20 0.56
MAPT P10636 6/20 0.56
GLA P06280 5/20 0.56
ALDH1A1 P00352 4/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HPGD P15428 3/20 0.56
PKM P14618 2/20 0.56
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
PIK3CA P42336 1/20 0.54
PI4KA P42356 1/20 0.54
PI4KB Q9UBF8 1/20 0.54
LMNA P02545 2/20 0.54
NFKB1 P19838 2/20 0.54
NFKB2 Q00653 2/20 0.54
RELA Q04206 2/20 0.54
APP P05067 10/20 0.52
NPC1 O15118 5/20 0.48
RAB9A P51151 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13241670 0.94 KDM4E (0.59) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL13241680 0.93 KDM4E (0.57) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL12408902 0.88 KDM4E (0.70) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL13645837 0.88 APP (0.60) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL13645798 0.88 MAPT (0.60) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL1100094 0.88 MAPT (0.60) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL13645790 0.88 MAPT (0.60) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL6704183 0.87 RAB9A (0.59) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL13645860 0.87 MAPT (0.59) KDM4EGAAMAPTGLAALDH1A1
SCHEMBL13645731 0.85 KDM4E (0.50) KDM4EGAAMAPTGLAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598666-B2 Organic electroluminescent device and luminescent material SANYO ELECTRIC CO., LTD. (JP) 2009-10-06 US disclosed
US-7598666-B2 Organic electroluminescent device and luminescent material SANYO ELECTRIC CO., LTD. (JP) 2009-10-06 US disclosed