SCHEMBL13645869

SCHEMBL13645869

CCCC(CCC)c1ccc(CN)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.53
ESR2 Q92731 2/20 0.53
HRH3 Q9Y5N1 1/20 0.42
LOXL2 Q9Y4K0 6/20 0.41
PSIP1 O75475 1/20 0.41
ABAT P80404 1/20 0.39
TAAR1 Q96RJ0 1/20 0.37
NOS3 P29474 2/20 0.36
NOS1 P29475 2/20 0.36
NOS2 P35228 2/20 0.36
HTR2A P28223 1/20 0.36
F10 P00742 1/20 0.34
F11 P03951 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19263423 0.84 NR1I2 (0.47) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL21755105 0.83 NR1I2 (0.46) ESR1ESR2HRH3PSIP1HTR2A
SCHEMBL13470621 0.82 ESR1 (0.50) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL24741509 0.81 HRH3 (0.41) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL28203923 0.81 LOXL2 (0.43) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL27523203 0.81 SLC2A1 (0.41) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL18924648 0.81 HRH3 (0.41) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL27523204 0.81 SLC2A1 (0.41) ESR1ESR2HRH3LOXL2PSIP1
SCHEMBL13593518 0.80 PNMT (0.42) ESR1ESR2LOXL2NOS3NOS1
SCHEMBL27508219 0.79 ESR1 (0.42) ESR1ESR2HRH3LOXL2PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009121456-A1 CATALYST FOR OLIGOMERIZATION OF ETHYLENE, METHOD FOR PREPARATION THEREOF AND PROCESS FOR OLIGOMERIZATION USING IT LINDE AG (DE) 2009-10-08 WO disclosed