Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018680 | 0.86 | CYP1A2 (0.69) | CYP1A2CYP2D6ALDH1A1POLBCHRNA7 | |
| SCHEMBL21766914 | 0.85 | CYP2D6 (0.65) | CYP1A2CYP2D6ALDH1A1POLBCYP2C19 | |
| SCHEMBL12994617 | 0.85 | ALDH1A1 (0.82) | CYP1A2ALDH1A1POLBCYP2C19CYP2C9 | |
| SCHEMBL8149995 | 0.85 | CYP1A2 (0.67) | CYP1A2CYP2D6ALDH1A1POLBMBTD1 | |
| SCHEMBL4993839 | 0.84 | CYP1A2 (0.67) | CYP1A2CYP2D6ALDH1A1POLBCHRNA7 | |
| SCHEMBL8235480 | 0.83 | ALDH1A1 (0.79) | CYP1A2ALDH1A1POLBCYP2C19CYP2C9 | |
| SCHEMBL13475706 | 0.83 | CYP1A2 (0.65) | CYP1A2CYP2D6ALDH1A1POLBCHRNA7 | |
| SCHEMBL4023975 | 0.83 | CYP1A2 (0.65) | CYP1A2CYP2D6ALDH1A1POLBCHRNA7 | |
| SCHEMBL4018355 | 0.82 | CYP1A2 (1.00) | CYP1A2CYP2D6ALDH1A1POLB | |
| SCHEMBL10458999 | 0.81 | GAA (0.74) | CYP1A2ALDH1A1POLBCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274246-A1 | AMIDE COMPOUND AND USE THEREOF | 成都分迪药业有限公司 | 2023-01-05 | — | — | WO | disclosed |
| US-7598244-B2 | [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-10-06 | — | — | US | disclosed |
| US-7598244-B2 | [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-10-06 | — | — | US | disclosed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | disclosed |
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010515-A1 | [1,2,4] Triazolo [1,5, a] pyrimidin-2-ylurea derivative and use thereof | HLA-C, TPMT, TAP1 | CYP1A2 1987/4885CYP2D6 1505/4885ALDH1A1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.