SCHEMBL13645964

SCHEMBL13645964

CN(CCN(C)c1ccc(/C=C/c2cccc[n+]2C)cc1)c1ccc(/C=C/c2cccc[n+]2C)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.52
MEN1 O00255 8/20 0.52
KMT2A Q03164 8/20 0.52
NPC1 O15118 5/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
HTT P42858 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
STAT3 P40763 1/20 0.52
PABPC1 P11940 2/20 0.51
EIF4H Q15056 1/20 0.51
APOBEC3A P31941 4/20 0.48
APOBEC3G Q9HC16 4/20 0.48
GFER P55789 4/20 0.47
KDM4A O75164 2/20 0.47
KDM2A Q9Y2K7 2/20 0.47
GAA P10253 2/20 0.46
LMNA P02545 1/20 0.45
ALPG P10696 1/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3868958 0.98 RAB9A (0.51) RAB9AMEN1KMT2ANPC1ALDH1A1
Hydrochloric Acid SCHEMBL3868953 0.98 RAB9A (0.51) RAB9AMEN1KMT2ANPC1ALDH1A1
Hydrochloric Acid SCHEMBL3868960 0.98 RAB9A (0.51) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL13645971 0.93 MEN1 (0.50) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL13043734 0.92 RAB9A (0.48) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL13043733 0.92 RAB9A (0.48) RAB9AMEN1KMT2ANPC1ALDH1A1
Iodide SCHEMBL31372368 0.90 RAB9A (0.52) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL10104048 0.90 RAB9A (0.47) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL12657258 0.86 RAB9A (0.43) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL5676661 0.86 MEN1 (0.69) RAB9AMEN1KMT2ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2018848-B2 Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. ORÉAL L (FR) 2016-08-31 EP disclosed
EP-2018848-B1 Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. OREAL (FR) 2013-01-09 EP disclosed
US-7601180-B2 Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye L'OREAL S.A. (FR) 2009-10-13 US disclosed
US-20090049621-A1 USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE L'OREAL S.A. (FR) 2009-02-26 US disclosed
EP-2018848-A2 Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. L'Oreal (FR) 2009-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090049621-A1 USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE KRT18, S100A4, S100P RAB9A 4477/4885MEN1 2692/4885KMT2A 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.