Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 3/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13646250 | 0.92 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNATP53RAB9A | |
| SCHEMBL3835037 | 0.90 | KDM4E (0.45) | KDM4ETDP1ALDH1A1LMNATP53 | |
| SCHEMBL2475910 | 0.89 | HDAC1 (0.50) | KDM4ETDP1ALDH1A1LMNATP53 | |
| SCHEMBL13646199 | 0.88 | ALDH1A1 (0.52) | KDM4ETDP1ALDH1A1LMNATP53 | |
| SCHEMBL13646274 | 0.84 | EPHX2 (0.45) | KDM4ETDP1ALDH1A1LMNATP53 | |
| SCHEMBL3834058 | 0.84 | KDM1A (0.41) | KDM4ETDP1ALDH1A1LMNATP53 | |
| SCHEMBL13646227 | 0.84 | TP53 (0.48) | ALDH1A1LMNATP53RAB9APOLB | |
| SCHEMBL3835546 | 0.82 | PIR (0.44) | KDM4EALDH1A1LMNATP53RAB9A | |
| SCHEMBL13646255 | 0.82 | HDAC1 (0.51) | KDM4EALDH1A1LMNATP53RAB9A | |
| SCHEMBL2475671 | 0.82 | TSHR (0.43) | KDM4ETDP1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |