Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475910 | 0.93 | HDAC1 (0.50) | HDAC1HDAC2KDM1AALDH1A1LMNA | |
| SCHEMBL2475826 | 0.93 | HDAC1 (0.53) | HDAC1HDAC2ALDH1A1LMNARAB9A | |
| SCHEMBL2506731 | 0.92 | ALDH1A1 (0.54) | HDAC1HDAC2ALDH1A1LMNARAB9A | |
| SCHEMBL4393216 | 0.91 | HDAC1 (0.52) | HDAC1HDAC2ALDH1A1LMNARAB9A | |
| SCHEMBL3835767 | 0.88 | HDAC1 (0.56) | HDAC1HDAC2ALDH1A1LMNARAB9A | |
| SCHEMBL2475440 | 0.88 | KDM1A (0.54) | HDAC1HDAC2KDM1AHSD17B10HDAC3 | |
| SCHEMBL3834058 | 0.87 | KDM1A (0.41) | KDM1AALDH1A1LMNARAB9ATP53 | |
| SCHEMBL3835176 | 0.87 | ALDH1A1 (0.56) | HDAC1HDAC2ALDH1A1LMNARAB9A | |
| SCHEMBL2473986 | 0.87 | HDAC1 (0.59) | HDAC1HDAC2ALDH1A1LMNARAB9A | |
| SCHEMBL2474439 | 0.86 | HDAC1 (0.53) | HDAC1HDAC2ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |