SCHEMBL3835767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2506731	0.96	ALDH1A1 (0.54)	HDAC1HDAC2LMNATP53NPC1
	SCHEMBL3835176	0.92	ALDH1A1 (0.56)	HDAC1HDAC2LMNATP53NPC1
	SCHEMBL2475826	0.91	HDAC1 (0.53)	HDAC1HDAC2LMNATP53NPC1
	SCHEMBL12250267	0.90	HSD17B10 (0.49)	HDAC1HDAC2LMNATP53NPC1
	SCHEMBL2504031	0.90	ATM (0.51)	HDAC1HDAC2LMNATP53HSD17B10
	SCHEMBL4393216	0.89	HDAC1 (0.52)	HDAC1HDAC2LMNATP53NPC1
	SCHEMBL2473915	0.89	HDAC1 (0.56)	HDAC1HDAC2LMNATP53NPC1
	SCHEMBL2476586	0.88	HSD17B10 (0.55)	HDAC1HDAC2LMNAMAPK1HSD17B10
	SCHEMBL2475852	0.88	OPRM1 (0.53)	HDAC1HDAC2TP53USP2HSD17B10
	SCHEMBL13646255	0.88	HDAC1 (0.51)	HDAC1HDAC2LMNATP53NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.