Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.56 |
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.52 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.52 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601866 | 0.83 | ENPP1 (0.53) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL31314844 | 0.81 | ENPP1 (0.72) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL8561474 | 0.81 | ENPP1 (0.73) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL28742775 | 0.81 | FGFR1 (0.65) | ENPP1FGFR1SLC22A6CYP3A4ADORA2A | |
| SCHEMBL8897180 | 0.80 | SLC22A6 (0.72) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| Pyrophosphoric Acid SCHEMBL10602251 | 0.80 | CYP3A4 (0.55) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL8895414 | 0.79 | SLC22A6 (0.70) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL8927904 | 0.79 | SLC22A6 (0.70) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL9569602 | 0.79 | ENPP1 (0.55) | ENPP1FGFR1SLC22A6CYP3A4NT5E | |
| SCHEMBL21518178 | 0.79 | CYP3A4 (0.76) | CYP3A4ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503800-B1 | TREATMENT AND PREVENTION OF TISSUE DAMAGE ASSOCIATED WITH INCREASED C-REACTIVE PROTEIN PRODUCTION | PENTRAXIN THERAPEUTICS LTD (GB) | 2009-10-28 | — | — | EP | disclosed |