Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.70 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
| ▸ | POLG | P54098 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.48 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.48 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | AHCY | P23526 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897180 | 0.99 | SLC22A6 (0.72) | SLC22A6FGFR1ENPP1CYP3A4NT5E | |
| SCHEMBL8895414 | 0.98 | SLC22A6 (0.70) | SLC22A6FGFR1ENPP1CYP3A4NT5E | |
| Adefovir SCHEMBL28511793 | 0.84 | FGFR1 (0.97) | SLC22A6FGFR1ENPP1CYP3A4ABCB11 | |
| SCHEMBL8709070 | 0.83 | FAP (0.56) | SLC22A6FGFR1ENPP1CYP3A4NT5E | |
| SCHEMBL8561474 | 0.82 | ENPP1 (0.73) | SLC22A6FGFR1ENPP1CYP3A4NT5E | |
| Adefovir SCHEMBL29365535 | 0.82 | FGFR1 (1.00) | SLC22A6FGFR1ENPP1CYP3A4ABCB11 | |
| Adefovir SCHEMBL49373 | 0.82 | FGFR1 (1.00) | SLC22A6FGFR1ENPP1CYP3A4ABCB11 | |
| Adefovir SCHEMBL3643715 | 0.81 | FGFR1 (0.97) | SLC22A6FGFR1ENPP1CYP3A4ABCB11 | |
| Adefovir SCHEMBL3639260 | 0.81 | FGFR1 (0.97) | SLC22A6FGFR1ENPP1CYP3A4ABCB11 | |
| Adefovir SCHEMBL439995 | 0.81 | FGFR1 (0.97) | SLC22A6FGFR1ENPP1CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688778-A | VIRICIDES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1997-11-18 | — | — | US | claimed |