Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | PI4KA | P42356 | 2/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.51 |
| ▸ | AHCY | P23526 | 7/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.48 |
| ▸ | POLG | P54098 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569486 | 0.86 | ENPP1 (0.51) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL13648201 | 0.79 | ENPP1 (0.65) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL12126374 | 0.75 | ADORA2A (0.54) | ENPP1CYP3A4ADORA2AADORA1PI4KA | |
| SCHEMBL8561474 | 0.75 | ENPP1 (0.73) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL9569621 | 0.75 | ENPP1 (0.59) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL9569556 | 0.75 | ENPP1 (0.59) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL28742775 | 0.74 | FGFR1 (0.65) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL8897180 | 0.74 | SLC22A6 (0.72) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A | |
| SCHEMBL2293264 | 0.74 | ADORA2A (0.68) | CYP3A4ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL8895414 | 0.73 | SLC22A6 (0.70) | ENPP1SLC22A6FGFR1CYP3A4ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | claimed |