Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.30 |
| ▸ | HTR2C | P28335 | 4/20 | 0.30 |
| ▸ | HTR2B | P41595 | 4/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15927301 | 0.68 | TAAR1 (0.41) | TAAR1HTR2AHTR2CHTR2BADRB1 | |
| SCHEMBL3569753 | 0.63 | — | — | |
| SCHEMBL504685 | 0.63 | TAAR1 (0.37) | TAAR1 | |
| SCHEMBL21465751 | 0.62 | HTR2C (0.43) | HTR2AHTR2CHTR2BSLC6A4KCNH2 | |
| SCHEMBL26620755 | 0.62 | CHRNB2 (0.39) | HTR2AHTR2CHTR2BADRB1HTR1A | |
| SCHEMBL26620745 | 0.62 | HTR2C (0.42) | HTR2AHTR2CHTR2BADRB1HTR1A | |
| SCHEMBL20670368 | 0.60 | TDO2 (0.34) | — | |
| SCHEMBL21465822 | 0.60 | MB (0.37) | HTR2AHTR2CHTR2BADRB1HTR1A | |
| SCHEMBL10653611 | 0.60 | CHRM3 (0.47) | TAAR1HTR2C | |
| SCHEMBL30303234 | 0.60 | HTR2C (0.46) | HTR2AHTR2CHTR2BADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009124746-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-10-15 | — | — | WO | disclosed |