Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23381625 | 0.77 | MEN1 (0.38) | — | |
| SCHEMBL15238087 | 0.77 | CDK2 (0.34) | — | |
| SCHEMBL23497442 | 0.77 | KDM4E (0.36) | KDM4EHTT | |
| SCHEMBL23381890 | 0.77 | — | — | |
| SCHEMBL14287457 | 0.70 | MEN1 (0.32) | KDM4E | |
| SCHEMBL10562544 | 0.69 | MAPT (0.36) | KDM4EHTT | |
| SCHEMBL20542249 | 0.68 | CYP11B2 (0.36) | KDM4E | |
| SCHEMBL13657247 | 0.67 | — | — | |
| SCHEMBL21754311 | 0.67 | KDM4E (0.42) | KDM4EHTTCSNK2A1 | |
| SCHEMBL17933797 | 0.64 | ALDH1A1 (0.41) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247501-A1 | PROTEIN KINASE INHIBITORS | POLARIS GROUP (TW) | 2009-10-01 | — | — | US | disclosed |
| US-7517882-B2 | Protein kinase inhibitors | POLARIS GROUP (CN) | 2009-04-14 | — | — | US | disclosed |
| US-20080070893-A1 | Protein Kinase Inhibitors | POLARIS GROUP (CN) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070893-A1 | Protein Kinase Inhibitors | MAP3K15, MAP3K20, MAP3K5 | KDM4E 1864/4885HTT 2466/4885CSNK2A1 482/4885 |
| US-20090247501-A1 | PROTEIN KINASE INHIBITORS | MAP3K15, MAP3K20, MAP3K5 | KDM4E 1864/4885HTT 2466/4885CSNK2A1 482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.