Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566258 | 0.84 | CA2 (0.53) | ALDH1A1CA2GABRA1GABRB2MAPT | |
| SCHEMBL2612593 | 0.84 | ESR1 (0.42) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL13652813 | 0.82 | ESR1 (0.38) | ESR1ESR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL13652814 | 0.82 | CYP3A4 (0.39) | ESR1ESR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL14566262 | 0.79 | CA2 (0.35) | ALDH1A1CA2GABRA1GABRB2ATM | |
| SCHEMBL13652815 | 0.78 | CYP3A4 (0.34) | ESR1ESR2ALDH1A1CYP3A4CNR1 | |
| SCHEMBL1276539 | 0.78 | CA2 (0.56) | ESR1ESR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL2612597 | 0.77 | SHBG (0.36) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL29904482 | 0.75 | NPC1 (0.41) | ESR1ESR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL20272359 | 0.75 | NPC1 (0.41) | ESR1ESR2ALDH1A1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246416-A1 | OPTICAL FILM, METHOD OF MANUFACTURING THE SAME, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | KONICA MINOLTA OPTO, INC. (JP) | 2009-10-01 | — | — | US | disclosed |