SCHEMBL13654079

SCHEMBL13654079

O=C1c2cccc3c2c(cc2c4ccccc4ccc32)C1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 5/20 0.40
CYP1A2 P05177 4/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
ALDH1A1 P00352 5/20 0.39
HPGD P15428 5/20 0.39
MAPK1 P28482 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ERBB2 P04626 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
SOS1 Q07889 2/20 0.39
PAX8 Q06710 1/20 0.39
MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21323946 0.88 ALDH1A1 (0.47) CYP1A2CYP2C9CYP2C19ALDH1A1HPGD
SCHEMBL24276180 0.76 RAB9A (0.37) ALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL10015036 0.72 CES1 (0.51) HPRT1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL20698681 0.72 ALDH1A1 (0.42) CYP1A2CYP2C9CYP2C19ALDH1A1HPGD
SCHEMBL6880786 0.71 ALDH1A1 (0.45) CYP1A2CYP2C9CYP2C19ALDH1A1HPGD
SCHEMBL17070126 0.70 MAPK1 (0.56) HPRT1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL2302722 0.70 ALDH1A1 (0.71) HPRT1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL21699094 0.69 CYP1B1 (0.43) CYP1A2ALDH1A1MEN1KMT2ALMNA
SCHEMBL12726414 0.69 ALDH1A1 (0.56) CYP1A2ALDH1A1HPGDMAPK1HIF1A
SCHEMBL28581429 0.69 HPRT1 (0.64) HPRT1CYP1A2CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009123344-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2009-10-08 WO disclosed