Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659497 | 0.93 | KDM4E (0.41) | ADRB1ADRB3KDM4EALDH1A1HDAC1 | |
| SCHEMBL399307 | 0.92 | NAMPT (0.41) | ADRB1ADRB3KDM4EALDH1A1HDAC2 | |
| SCHEMBL13654999 | 0.91 | KDM4E (0.49) | KDM4EALDH1A1 | |
| SCHEMBL13655001 | 0.90 | HIF1A (0.42) | ADRB1ADRB3HDAC1HDAC2 | |
| SCHEMBL13659667 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1 | |
| SCHEMBL10286662 | 0.84 | NAMPT (0.43) | ADRB1ADRB3KDM4EALDH1A1HDAC1 | |
| SCHEMBL404283 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1 | |
| SCHEMBL461339 | 0.83 | HDAC1 (0.48) | HDAC1HDAC2 | |
| SCHEMBL13659688 | 0.83 | ADRB3 (0.42) | ADRB1ADRB3HDAC1HDAC2 | |
| SCHEMBL403647 | 0.82 | HIF1A (0.47) | ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | ADRB1 1968/4885ADRB3 3223/4885KDM4E 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.