Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 15/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232425 | 0.92 | SOAT1 (0.50) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL4064015 | 0.91 | HDAC1 (0.40) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL4066145 | 0.79 | HDAC1 (0.41) | HDAC1HDAC3HDAC2 | |
| SCHEMBL4236771 | 0.77 | SOAT1 (0.59) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL4059594 | 0.77 | ALDH1A1 (0.47) | HDAC1HDAC3HDAC2HTT | |
| SCHEMBL4056220 | 0.76 | HDAC1 (0.47) | HDAC1HDAC3HDAC2HTT | |
| SCHEMBL4237117 | 0.75 | SMARCA2 (0.40) | HDAC1 | |
| SCHEMBL4240863 | 0.75 | PLK1 (0.47) | — | |
| SCHEMBL4064859 | 0.74 | RAB9A (0.47) | HDAC1HDAC3HDAC2HDAC10HDAC6 | |
| SCHEMBL4055538 | 0.74 | HDAC8 (0.44) | HDAC1HDAC3HDAC2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |